Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial
The effect of midazolam as premedication on the quality of postoperative recovery after laparotomy: a randomized clinical trial.
Despite the uncertain effects of anxiolytic premedication with benzodiazepines on the quality of postoperative recovery, perioperative benzodiazepine administration is still a common practice in many hospitals. We evaluated the effect of premedication with midazolam on the quality of recovery in hospitalized patients undergoing a laparotomy. ⋯ Administration of midazolam as premedication for laparotomy patients did not improve the quality of recovery up to one week after surgery. General prescription of midazolam as premedication can be questioned and might only suit some patients.
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Review
Restrictive fluid management strategies and outcomes in liver transplantation: a systematic review.
Restrictive fluid management strategies have been proposed to reduce complications in liver transplant recipients. We conducted a systematic review to evaluate the effects of restrictive perioperative fluid management strategies, compared with liberal ones, on postoperative outcomes in adult liver transplant recipients. Our primary outcome was acute kidney injury (AKI). Our secondary outcomes were bleeding, mortality, and other postoperative complications. ⋯ Based on low or very low levels of evidence, we did not find any association between restrictive fluid management strategies and AKI, but we observed possible protective effects of intraoperative restrictive fluid management strategies on other outcomes.
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50% of retracted anesthesiology papers are retracted because of fraud, and 30% because of inadequate ethics approval.
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