The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Jun 2007
Determination of extended-interval gentamicin dosing for neonatal patients in developing countries.
Infectious diseases account for an estimated 36% of neonatal deaths globally. The purpose of this study was to determine safe, effective, simplified dosing regimens of gentamicin for treatment of neonatal sepsis in developing countries. ⋯ Safe, therapeutic gentamicin dosing regimens were identified for treatment of neonatal sepsis in developing country settings. Administration of these doses could be simplified through use of Uniject, a prefilled, single injection device designed to make injections safe and easy to deliver in developing country settings.