The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Jan 2010
Randomized Controlled Trial Comparative StudyA randomized, double-blind study examining the comparative efficacies and safety of inhaled epinephrine and nasal decongestant in hospitalized infants with acute bronchiolitis.
Optimal treatment of acute bronchiolitis is currently unclear. In a double-blind study, we found no significant differences between inhaled epinephrine and nasal decongestant in hospitalized infants with acute bronchiolitis regarding length of hospitalization, need for oxygen supplementation, or intravenous fluids and clinical score. Nasal decongestant is as effective as inhaled epinephrine in acute bronchiolitis.
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Pediatr. Infect. Dis. J. · Jan 2010
Review Case ReportsItraconazole treatment of nonmeningeal coccidioidomycosis in children: two case reports and review of the literature.
Coccidioides immitis causes a wide range of disease in humans. Fluconazole and itraconazole are effective treatments. ⋯ We report 2 cases of coccidioidomycosis involving bone in children successfully treated with itraconazole oral solution. Itraconazole oral solution is effective in treating nonmeningeal coccidioidomycosis in children, particularly skeletal disease, and infections that are refractory to fluconazole.
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Pediatr. Infect. Dis. J. · Jan 2010
Blood culture and bacteremia predictors in infants less than three months of age with fever without source.
(1) To assess the rate of bacteremia in febrile infants less than 3 months of age admitted to a pediatric emergency department at a tertiary hospital; (2) to describe the bacteria isolated; and (3) to analyze factors related to increased probability of having a positive blood culture. ⋯ A positive blood culture rate of 2.2% was found in infants less than 3 months of age with FWS. C-reactive protein, white blood cell count, and absolute neutrophil count were not good bacteremia predictors. We recommend obtaining a blood culture in infants less than 3 months of age with FWS, particularly those patients considered "not well-appearing" and those with leukocyturia and/or nitrituria.