The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Jan 2013
Evaluation of CD64 expression on neutrophils as an early indicator of neonatal sepsis.
Enhanced neutrophil CD64 (nCD64) expression is likely to be useful in diagnosis of neonatal sepsis. This study evaluated the diagnostic efficacy of nCD64 expression as an early indicator of neonatal sepsis. ⋯ Enhanced nCD64 reported as median M/N CD64 ratio is a highly sensitive marker of culture-positive neonatal sepsis. It additionally identifies a separate group among culture-negative sick neonates and may be useful to guide antibiotic administration especially in these neonates.
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Pediatr. Infect. Dis. J. · Jan 2013
ReviewTopical umbilical cord care for prevention of infection and neonatal mortality.
Umbilical cord care varies often reflecting community or health-worker beliefs. We undertook a review of current evidence on topical umbilical cord care. Study quality was assessed using the Grading of Recommendations, Assessment, Development and Evaluation system, and a meta-analysis was conducted for comparable trials. Available moderate-quality to high-quality evidence indicate that cord cleansing with 4% chlorhexidine may reduce the risk of neonatal mortality and sepsis (omphalitis) in low-resource settings.
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Pediatr. Infect. Dis. J. · Jan 2013
Impact of respiratory viral infections on α-hemolytic streptococci and otopathogens in the nasopharynx of young children.
We studied nasopharyngeal (NP) colonization in a cohort of children to determine the impact of viral upper respiratory infections (URIs) on nonpneumococcal α-hemolytic streptococci (AHS) and otopathogen colonization in association with acute otitis media (AOM). ⋯ Respiratory viral infections alter NP carriage rates of commensal AHS and otopathogens, including before AOM.
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Pediatr. Infect. Dis. J. · Jan 2013
Factors affecting human papillomavirus vaccine use among White, Black and Latino parents of sons.
Although human papillomavirus (HPV) vaccination has been available for males since 2009, its uptake remains low. In light of new recommendations for universal vaccination of males, understanding parental attitudes toward this vaccine is important. This study aimed to describe HPV-related knowledge and intention to accept HPV vaccination among White, Black and Latino parents of sons and to assess vaccination rates among their sons. ⋯ Although parents in our study had limited understanding of HPV disease in males, most would vaccinate their sons if recommended by their physicians.