The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Oct 2017
Serious Bacterial Infections in Hospitalized Febrile Infants in the First and Second Months of Life.
Most protocols evaluating serious bacterial infection (SBI) risk in febrile infants classify neonates <30 days of age as high risk (HR), while other protocols do not distinguish between infants <30 and 30-60 days of age. We compared SBI rates in febrile infants at the first and the second months of life. ⋯ In HR infants, higher SBI rates were associated with younger age, higher body temperature and thrombocytopenia. In contrast, SBI (mostly urinary tract infection) rates among LR infants (approximately 10%) were not associated with these factors.
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Pediatr. Infect. Dis. J. · Oct 2017
Trends in Diagnoses Among Hospitalizations of HIV-infected Children and Adolescents in the United States: 2003-2012.
Using data from 2003-2012, we updated a previous analysis of trends in hospitalizations of HIV-infected children and adolescents in the United States. ⋯ The number of hospitalizations for HIV-infected children declined from 2003 to 2012. The decreased prevalence of several discharge diagnoses and lower risk of death during hospitalization likely reflect improvements in HIV therapies and increased uptake of other preventive strategies. However, the increasing prevalence of discharge diagnoses for bacterial infections/sepsis warrants further attention and monitoring.
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Pediatr. Infect. Dis. J. · Oct 2017
Management of Pediatric Perforated Appendicitis: Comparing Outcomes Using Early Appendectomy Versus Solely Medical Management.
There is controversy regarding whether children with perforated appendicitis should receive early appendectomy (EA) versus medical management (MM) with antibiotics and delayed interval appendectomy. The objective of this study was to compare outcomes of children with perforated appendicitis who receive EA versus MM. ⋯ Children with perforated appendicitis who receive EA experience significantly less morbidity and complications versus those receiving MM. The theoretical concern for enhanced morbidity associated with EA management of perforated appendicitis is not supported by our analysis.