The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Oct 2018
HLA-DR Expression on Monocyte Subsets in Critically Ill Children.
To longitudinally study blood monocyte subset distribution and human leukocyte antigen-DR (HLA-DR) expression on monocyte subsets in children with sepsis, post-surgery and trauma in relation to nosocomial infections and mortality. ⋯ Monocytic HLA-DR expression decreased during PICU stay and was lower compared with controls on all examined time points, especially on classical monocytes and in children admitted for sepsis. Low HLA-DR expression on classical monocytes was associated with nosocomial infections and death.