The Pediatric infectious disease journal
-
Pediatr. Infect. Dis. J. · Jul 2019
Observational StudyOutcomes of Congenital Zika Virus Infection During an Outbreak in Valle del Cauca, Colombia.
Despite increasing information in the literature regarding congenital Zika infection, gaps remain in our knowledge of its clinical manifestations. ⋯ We observed a high frequency of gestational and neonatal complications in pregnant women who acquired Zika infection, especially in early pregnancy, resulting in a broad spectrum of clinical manifestations. Preventive measures are urgently needed to reduce the clinical burden during future Zika outbreaks.
-
Pediatr. Infect. Dis. J. · Jul 2019
A Population-based Observational Study of Childhood Encephalitis in Children Admitted to Pediatric Intensive Care Units in England and Wales.
Encephalitis is a serious neurologic condition that can result in admission to intensive care. Yet, there are no studies on pediatric intensive care unit (PICU) admission rates and usage of intensive care resources by children with encephalitis in England and Wales. The objectives of this study were to (1) define the PICU incidence and mortality rates for childhood encephalitis, (2) describe the usage of intensive care resources by children with encephalitis admitted to PICU and (3) explore the associated cost from PICU encephalitis admissions. ⋯ These data suggest that encephalitis places a significant burden to the healthcare service. More work is needed to improve outcomes for children with encephalitis.