Critical care medicine
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Critical care medicine · Oct 1992
Myocardial metabolism and adaptation during extreme hemodilution in humans after coronary revascularization.
This study was designed to evaluate the oxygen transport adjustments and myocardial metabolic adaptation that occurs with different levels of hemodilution during normothermia after cardiopulmonary bypass. ⋯ Hemodilution to a hematocrit of approximately 15% is tolerated in anesthetized humans after coronary artery bypass surgery. There was no evidence of myocardial ischemia, as demonstrated by absence of S-T depression on the electrocardiogram, lactate extraction, or hypoxanthine release. In selected patients, postoperative transfusion may be based on systemic physiologic end-points, such as oxygen extraction ratio, rather than set hematocrit values.
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Critical care medicine · Oct 1992
Randomized Controlled Trial Comparative Study Clinical TrialEffect of acidified enteral feedings on gastric colonization in the critically ill patient.
To evaluate the effect of acidified enteral nutritional formulas (feedings) on gastric colonization and pH in critically ill patients. ⋯ Acidified enteral feedings are effective in eliminating and preventing gastric colonization in critically ill patients. Further investigation is needed to assess its effect on nosocomial infection rates.