Critical care medicine
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Critical care medicine · Jun 1992
Comparative StudyRelationship between hepatic blood flow and tissue lipid peroxidation in the early postburn period.
To determine the effect of a body burn on effective or nutrient liver blood flow and the relationship between blood flow and oxidant-induced lipid peroxidation. ⋯ Effective liver blood flow is markedly decreased after burn injury, even with apparently adequate volume resuscitation, when using lactated Ringer's solution. Liver lipid peroxidation persists even when effective liver blood flow is maintained, indicating that the oxidant process is not solely related to blood flow. Infusion of the antioxidant deferoxamine during resuscitation not only prevents the lipid peroxidation, most likely by a nonblood-flow-related process, but also results in an increase in blood flow above normal rates, suggesting that postburn liver oxygen needs exceed normal values.
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Critical care medicine · Jun 1992
Cerebral blood flow pattern and autoregulation during open-heart surgery in infants and young children: a transcranial, Doppler ultrasound study.
To elucidate the effect of cardiopulmonary bypass on cerebral perfusion and on the autoregulatory ability of the cerebral vascular bed of infants and young children. ⋯ The finding suggests that cerebral blood flow decreases with decreasing nasopharyngeal temperature. During hypothermic cardiopulmonary bypass, cerebral autoregulation seems to be easily disturbed, especially at low nasopharyngeal temperatures.
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Critical care medicine · Jun 1992
Outcome of intensive care of the "oldest-old" critically ill patients.
To determine the short-term and long-term outcome of critically ill "oldest-old" (greater than or equal to 85 yrs) patients. ⋯ These findings suggest that age alone may be an inappropriate criterion for allocation of ICU resources.