Critical care medicine
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Critical care medicine · Oct 1999
Editorial Comment ReviewPhysician variability in limiting life-sustaining treatment.
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Critical care medicine · Oct 1999
Comparative Study Clinical TrialMyocardial ischemia and weaning failure in patients with coronary artery disease: an update.
To determine the frequency and effects of weaning-related myocardial ischemia on weaning outcomes in patients with coronary artery disease. ⋯ Electrocardiographic evidence of myocardial ischemia occurs frequently and is associated with significantly increased risk of first-day weaning failure in patients with coronary artery disease.
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Critical care medicine · Oct 1999
Comparative StudySubcutaneous administration of fentanyl and midazolam to prevent withdrawal after prolonged sedation in children.
To determine the efficacy of switching to subcutaneous fentanyl with or without midazolam to prevent withdrawal after prolonged sedation in children in the pediatric intensive care unit (PICU). ⋯ The subcutaneous route provides an effective alternative to intravenous administration. It allows for gradual weaning from sedative/analgesic agents after prolonged sedation while eliminating the need to maintain intravenous access.
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Critical care medicine · Oct 1999
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialContinuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group.
To assess the effect of plasmafiltration (PF) on biochemical markers of inflammation, cytokines, organ dysfunction, and 14-day mortality in human sepsis. ⋯ PF caused a significant attenuation of the acute-phase response in sepsis. There was no significant difference in mortality, but there was a trend toward fewer organs failing in the PF group that suggests that this procedure might be beneficial.