Critical care medicine
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Critical care medicine · May 2012
Randomized Controlled TrialRight ventricular function during high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome.
To evaluate the effect of mean airway pressure under high-frequency oscillatory ventilation on right ventricular function. ⋯ In patients with mainly pulmonary acute respiratory distress syndrome, using high mean airway pressure under high-frequency oscillatory ventilation can worsen right ventricular function when compared with protective conventional mechanical ventilation, notably in patients in whom high-frequency oscillatory ventilation produced less alveolar recruitment of the posterior parts of the lungs. This study highlights the interest of monitoring right ventricular function during high-frequency oscillatory ventilation.
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Critical care medicine · May 2012
Randomized Controlled Trial Multicenter StudyOccurrence and impact of intracranial pressure elevation during treatment of severe intraventricular hemorrhage.
Elevated intracranial pressure is one of the proposed mechanisms leading to poor outcomes in patients with intraventricular hemorrhage. We sought to characterize the occurrence and significance of intracranial hypertension in severe intraventricular hemorrhage requiring extraventricular drainage. ⋯ Intracranial pressure is not frequently elevated during monitoring and drainage with an extraventricular drainage in patients with severe intraventricular hemorrhage, although intracranial pressure >30 mm Hg predicts higher short-term mortality. Thrombolytic therapy may reduce the frequency of high intracranial pressure events. Intracranial pressure elevation appears to be significantly correlated with extraventricular drainage placement in the ventricle with greatest clot volume.