Critical care medicine
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Critical care medicine · Feb 2014
Editorial CommentDefining an Intermediate Step in End-of-Life Therapy*.
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Critical care medicine · Feb 2014
Multicenter StudyConsulting Communities When Patients Cannot Consent: A Multicenter Study of Community Consultation for Research in Emergency Settings.
To assess the range of responses to community consultation efforts conducted within a large network and the impact of different consultation methods on acceptance of exception from informed consent research and understanding of the proposed study. ⋯ Interactive community consultation methods were associated with increased acceptance of exception from informed consent and greater overall recall of study information but lower recall of risks. There was also significant variability in exception from informed consent acceptance among different interactive consultation events. These findings have important implications for institutional review board and investigators conducting exception from informed consent research and for community engagement efforts in research more generally.
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Critical care medicine · Feb 2014
Observational StudyImproving Code Team Performance and Survival Outcomes: Implementation of Pediatric Resuscitation Team Training.
To determine whether implementation of Composite Resuscitation Team Training is associated with improvement in survival to discharge and code team performance after pediatric in-hospital cardiopulmonary arrest. ⋯ With implementation of Composite Resuscitation Team Training, survival to discharge after pediatric cardiopulmonary arrest improved, as did code team performance. Demonstration of improved survival after adjusting for code team adherence to resuscitation standards suggests that this may be a valuable resuscitation training program. Further studies are needed to determine causality and generalizability.
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Critical care medicine · Feb 2014
Intraosseous Lipid Emulsion: An Effective Alternative to IV Delivery in Emergency Situations.
To determine whether intraosseous infusion of a lipid emulsion reverses cardiac pharmacotoxicity in anaesthetized rats. ⋯ These proof-of-principle data indicate that intraosseous infusion of lipid emulsion rapidly reverses bupivacaine-induced cardiac toxicity in rats. Further studies are warranted to optimize this novel route of lipid emulsion injection in emergency situations when intravascular access is not secured.