Critical care medicine
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Critical care medicine · Feb 2021
Meta AnalysisEffectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis.
To evaluate the impact of bundle interventions on ICU delirium prevalence, duration, and other patients' adverse outcomes. ⋯ This meta-analysis fails to support that bundle interventions are effective in reducing ICU delirium prevalence and duration, but supports that bundle interventions are effective in reducing the proportion of patient-days with coma, hospital length of stay, and 28-day mortality. Larger randomized clinical trials are needed to evaluate the impact of bundle interventions on ICU delirium and other clinical outcomes.