Critical care medicine
The most recent articles from:
Crit. Care Med.
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Critical care medicine · Sep 1993
Randomized Controlled Trial Clinical TrialEffects of blood transfusion on oxygen transport variables in severe sepsis.
To investigate whether increasing oxygen delivery (DO2) by increasing hematocrit results in increases in oxygen uptake (VO2) in septic patients with an abnormal DO2/VO2 relationship. ⋯ In patients with an abnormal DO2-dependent VO2, as shown by increases in VO2 brought about by an infusion of dobutamine, blood transfusion does not significantly increase VO2, despite significant changes in DO2. The VO2, in some critically ill patients, depends more on blood flow than on global DO2.