The Journal of head trauma rehabilitation
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J Head Trauma Rehabil · Mar 2003
ReviewThe use of atypical antipsychotics in traumatic brain injury.
The use of antipsychotic medication in treating individuals with traumatic brain injury (TBI) has been controversial. Much of the caution derives from animal studies (and limited human data) with regard to typical antipsychotics. ⋯ In this article, mechanisms of action of typical and atypical antipsychotics are discussed, with particular attention paid to their use in TBI. Indications and contraindications are presented, and recommendations are made for the responsible prescribing of antipsychotic medications after TBI.