The Journal of head trauma rehabilitation
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J Head Trauma Rehabil · Jan 2017
Review Comparative StudyNeuroimaging in Blast-Related Mild Traumatic Brain Injury.
To summarize imaging findings in blast-related mild traumatic brain injury. ⋯ Vast variation in the sample, design, and measurement features across studies precludes salient conclusions regarding the effectiveness of neuroimaging to assess outcomes and elucidate pathomechanisms. The inherent spatial heterogeneity of mild traumatic brain injury pathology presents a major challenge to meaningful convergence across and generalizable inferences. Approaches to standardize methodology and facilitate access to data and integration across studies hold promise for enhancing our understanding of this complex brain disorder, but can only bear fruit if they are actually consistently implemented.