Epilepsy research
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Dose-response effect of levetiracetam 1000 and 2000 mg/day in partial epilepsy.
To evaluate the efficacy, dose-response, tolerability, and withdrawal effects of levetiracetam (Keppra) as adjunctive therapy in adult patients with partial epilepsy. ⋯ Levetiracetam was effective and well-tolerated and decreased seizure frequency in a dose-dependent manner, with no evidence of typical withdrawal-related adverse events or rebound phenomena after withdrawal or down-titration.