Journal of Korean medical science
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J. Korean Med. Sci. · Feb 2023
ReviewComparison of Trends in the Incidence of Traumatic Spinal Cord Injury in Daily Life, Automobile Accidents, and Industrial Accidents: A National Multi-Insurance Study in Korea.
To examine the incidence of traumatic spinal cord injury (TSCI) from all etiologies, we measured and compared the incidence of TSCI from three national or quasi-national databases in South Korea, namely, the National Health Insurance Service (NHIS), automobile insurance (AUI), and Industrial Accident Compensation Insurance (IACI). ⋯ The differences in trends in the incidence of TSCI may be due to the different etiologies and different characteristics of subjects depending on insurance type. These results imply the need for tailored medical strategies for the different injury mechanisms represented by three national insurance services in South Korea.
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J. Korean Med. Sci. · Feb 2023
ReviewOptimal Use and Need for Therapeutic Drug Monitoring of Teicoplanin in Children: A Systematic Review.
Teicoplanin is a glycopeptide antimicrobial that treats serious invasive infections caused by gram-positive bacteria, such as the methicillin-resistant Staphylococcus aureus. Despite some comparable advantages, there is no guideline or clinical recommendation for teicoplanin in the pediatric population, unlike vancomycin where abundant studies and the recently revised guideline on therapeutic drug level monitoring (TDM) exist. ⋯ Current evidence on teicoplanin trough levels in pediatric populations is insufficient due to heterogeneity. However, target trough levels with favorable clinical efficacy are achievable by recommended dosing regimen in the majority of patients.
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J. Korean Med. Sci. · Feb 2023
Relationship Between the Serum FGF21 Level and Growth in Children of Short Stature.
This study investigated the relationship between fibroblast growth factor 21 (FGF21) levels and growth in children with growth hormone deficiency (GHD) and idiopathic short stature (ISS), and the effects of the FGF21 level on response to growth hormone (GH) treatment. ⋯ The FGF21 level was higher in children of short stature, both those with GHD and the ISS, than in children with normal growth. The pretreatment FGF21 level negatively affected the GV of children with GH-treated GHD. These results suggest the existence of a GH/FFA/FGF21 axis in children.
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J. Korean Med. Sci. · Feb 2023
Randomized Controlled TrialA Classifying Model of Obstructive Sleep Apnea Based on Heart Rate Variability in a Large Korean Population.
The majority of patients with obstructive sleep apnea do not receive timely diagnosis and treatment because of the complexity of a diagnostic test. We aimed to predict obstructive sleep apnea based on heart rate variability, body mass index, and demographic characteristics in a large Korean population. ⋯ Obstructive sleep apnea was fairly predicted by using heart rate variability, body mass index, and demographic characteristics in a large Korean population. Prescreening and continuous treatment monitoring of obstructive sleep apnea may be possible simply by measuring heart rate variability.