Journal of Korean medical science
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J. Korean Med. Sci. · Dec 2015
Human Urine-derived Stem Cells Seeded Surface Modified Composite Scaffold Grafts for Bladder Reconstruction in a Rat Model.
We conducted this study to investigate the synergistic effect of human urine-derived stem cells (USCs) and surface modified composite scaffold for bladder reconstruction in a rat model. The composite scaffold (Polycaprolactone/Pluronic F127/3 wt% bladder submucosa matrix) was fabricated using an immersion precipitation method, and heparin was immobilized on the surface via covalent conjugation. ⋯ In histological and immunohistochemical analysis, the USC-scaffold(heparin-bFGF) group showed pronounced, well-differentiated, and organized smooth muscle bundle formation, a multi-layered and pan-cytokeratin-positive urothelium, and high condensation of submucosal area. The USCs seeded scaffold(heparin-bFGF) exhibits significantly increased bladder capacity, compliance, regeneration of smooth muscle tissue, multi-layered urothelium, and condensed submucosa layers at the in vivo study.
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J. Korean Med. Sci. · Nov 2015
ReviewWho Neglects Neglected Tropical Diseases? - Korean Perspective.
Neglected tropical diseases (NTDs) are a group of tropical infectious diseases of poorest people. Of 17 NTDs managed by WHO, two, guinea worm disease (by 2015) and yaws (by 2020) are targeted for eradication, and four (blinding trachoma, human African trypanosomiasis, leprosy, and lymphatic filariasis) for elimination by 2020. The goals look promising but 11 others are still highly prevalent. ⋯ After the millennium development goals declared disease control over the world, NTDs are becoming less neglected globally. Even with limited resources, beginning a sustainable national program is the key for the control and elimination of NTDs. No more neglect, especially no more self-neglect, can eliminate diseases and upgrade quality of life of the neglected people.
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J. Korean Med. Sci. · Nov 2015
Horizontal Inequity in Elderly Health Care Utilization: Evidence from India.
Against the backdrop of population aging, this paper presents the analysis of need-standardised health care utilization among elderly in India. Based on nationally representative morbidity and health care survey 2004, we demonstrate that the need for health care utilization is indeed pro-poor in nature. However, the actual health care utilization is concentrated among richer sections of the population. ⋯ We also find that the distribution of elderly across social groups and their educational achievements favours the rich and significantly contributes to overall inequality. Nevertheless, contribution of need-related self-assessed health clearly favours pro-poor inequality. In concluding, we argue that to reduce such inequities in health care utilization it is necessary to increase public investments in health care infrastructure including geriatric care particularly in rural areas and underdeveloped regions to enhance access and quality of health care for the elderly.
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Critical (or intensive) care medicine (CCM) is a branch of medicine concerned with the care of patients with potentially reversible life-threatening conditions. Numerous studies have demonstrated that adequate staffing is of crucial importance for patient outcome. Adequate staffing also showed favorable cost-effectiveness in terms of ICU stay, decreased use of resources, and lower re-admission rates. ⋯ The global pandemic episodes in the past decade showed that our society is not well prepared for severe illnesses or mass casualty. To improve CCM in Korea, reimbursement of the government must be amended such that referral hospitals can hire sufficient number of qualified intensivists and nurses. For the government to address these urgent issues, public awareness of the role of CCM is also required.
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J. Korean Med. Sci. · Nov 2015
ReviewPreserving the Integrity of Citations and References by All Stakeholders of Science Communication.
Citations to scholarly items are building bricks for multidisciplinary science communication. Citation analyses are currently influencing individual career advancement and ranking of academic and research institutions worldwide. This article overviews the involvement of scientific authors, reviewers, editors, publishers, indexers, and learned associations in the citing and referencing to preserve the integrity of science communication. ⋯ Few editorial associations have dealt with the issue of citations and properly managed references. As a prime example, the International Committee of Medical Journal Editors (ICMJE) issued in December 2014 an updated set of recommendations on the need for citing primary literature and avoiding unethical references, which are applicable to the global scientific community. With the exponential growth of literature and related references, it is critically important to define functions of all stakeholders of science communication in curbing the issue of irrational and unethical citations and thereby improve the quality and indexability of scholarly journals.