European journal of haematology
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Multicenter Study
Multicentered patient-based evidence of the role of free light chain ratio normalization in multiple myeloma disease relapse.
The normalization of free light chain ratio (FLCr) has been introduced as a marker of stringent complete remission (CR) of multiple myeloma (MM). There is currently a lack of literature assessing the role of FLCr on MM disease progression and remission status. ⋯ We did not observe any benefit from FLCr normalization in CR in myeloma patients in terms of progression-free survival or overall survival.