Journal of the American Academy of Child and Adolescent Psychiatry
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J Am Acad Child Adolesc Psychiatry · May 2012
Review Meta AnalysisAdvancing maternal age is associated with increasing risk for autism: a review and meta-analysis.
We conducted a meta-analysis of epidemiological studies investigating the association between maternal age and autism. ⋯ The results of this meta-analysis support an association between advancing maternal age and risk of autism. The RR increased monotonically with increasing maternal age. The association persisted after the effects of paternal age and other potential confounders had been considered, supporting an independent relation between higher maternal age and autism.