Journal of the American Academy of Child and Adolescent Psychiatry
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We thank Dr. Shaligram, author of this Letter to the Editor, for the interest in our recent article reporting time-dependent effects of prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) on behavioral, emotional, and social development in offspring at age 5 years.1 Dr. Shaligram raises interesting points of consideration for interpretation of the study results, and poses methodological questions about our window of exposure classification.2.
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J Am Acad Child Adolesc Psychiatry · Sep 2018
Comment LetterEffect of Selective Serotonin Reuptake Inhibitor Use in Pregnancy on Emotional Health of Children.
I read with interest the article by Lupattelli et al., "Effect of Time-Dependent Selective Serotonin Reuptake Inhibitor Antidepressants During Pregnancy on Behavioral, Emotional, and Social Development in Preschool-Aged Children,"1 which describes the effects of selective serotonin reuptake inhibitor (SSRI) use in pregnancy on mental health in offspring, in the March issue of the Journal. The investigators found that SSRI use in late pregnancy resulted in greater risk for anxious/depressed behaviors in children by 5 years of age compared with unexposed children.