Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · May 2005
Seasonality of vitamin D status and bone turnover in patients with Crohn's disease.
While winter-time vitamin D deficiency has been well-documented in Crohn's disease patients, less is known about vitamin D status during summertime and whether a seasonal variation exists in bone turnover. ⋯ There were notable seasonal variations in vitamin D status and bone turnover markers in Crohn's disease patients. The impact of winter decline in vitamin D status and increase in bone turnover on long-term risk of osteopenia/osteoporosis in Crohn's disease patients is unclear.