Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Oct 2007
Randomized Controlled Trial Multicenter StudyClinical trial: effect of mitemcinal (a motilin agonist) on gastric emptying in patients with gastroparesis - a randomized, multicentre, placebo-controlled study.
Mitemcinal is an orally active motilin agonist that could potentially improve gastric emptying. ⋯ Mitemcinal is capable of accelerating gastric emptying in both diabetic and idiopathic patients with gastroparesis.
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Aliment. Pharmacol. Ther. · Oct 2007
Comparative StudyProspective evaluation of faecal neutrophil-derived proteins in identifying intestinal inflammation: combination of parameters does not improve diagnostic accuracy of calprotectin.
Differentiating symptoms of irritable bowel syndrome from those of organic intestinal disease is a common clinical problem. Several neutrophil-derived proteins have been proposed as a marker of inflammatory bowel disease. ⋯ Although all faecal biomarkers studied provide a reliable and simple non-invasive means in the differentiation of inflammatory bowel disease and irritable bowel syndrome, calprotectin appears to represent the most accurate marker to discriminate between these two common causes of chronic diarrhoea.