Alimentary pharmacology & therapeutics
-
Aliment. Pharmacol. Ther. · Mar 2007
Randomized Controlled Trial Multicenter StudyAn open-label study of chronic polyethylene glycol laxative use in chronic constipation.
Polyethylene glycol 3350 (MiraLAX, Braintree Laboratories Inc., Braintree, MA, USA) is approved for the short-term treatment of occasional constipation. ⋯ Polyethylene glycol laxative is safe and effective for treating constipation in adult and elderly patients for periods up to 12 months, with no evidence of tachyphylaxis.
-
Aliment. Pharmacol. Ther. · Mar 2007
Meta AnalysisMeta-analysis: randomized controlled trials of clindamycin/aminoglycoside vs. beta-lactam monotherapy for the treatment of intra-abdominal infections.
To compare the effectiveness and safety of clindamycin/aminoglycoside with broad-spectrum beta-lactam monotherapy in patients with intra-abdominal infections by performing a meta-analysis of randomized controlled trials (RCTs). ⋯ The results of our meta-analysis suggest that beta-lactams are more effective in the treatment of intra-abdominal infections compared with clindamycin/aminoglycoside.