Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Jul 2013
Randomized Controlled TrialVitamin E and changes in serum alanine aminotransferase levels in patients with non-alcoholic steatohepatitis.
Non-alcoholic steatohepatitis (NASH) is a common cause of serum alanine aminotransferase (ALT) elevations and chronic liver disease, but it is unclear how well ALT elevations reflect the liver injury. ⋯ NCT00063622.
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Aliment. Pharmacol. Ther. · Jul 2013
Young adults with coeliac disease may be at increased risk of early atherosclerosis.
Accelerated progression of atherosclerosis and increased cardiovascular risk have been described in immune-mediated disorders, but few data are available in coeliac disease. ⋯ Adults with coeliac disease seem to be at potentially increased risk of early atherosclerosis as suggested by vascular impairment and unfavourable biochemical risk pattern. Chronic inflammation might play a determining role. Gluten abstinence with mucosal normalisation reverts to normal the observed alterations.