Alimentary pharmacology & therapeutics
-
Aliment. Pharmacol. Ther. · Jun 2003
Conscious sedation with propofol in elderly patients: a prospective evaluation.
To characterize the safety of endoscopic procedures and propofol use as administered by nurses in a cohort of elderly patients. ⋯ This present study documents that gastrointestinal endoscopic procedures are safe and well tolerated even in the very elderly. Nurse-administered propofol is a safe and reasonable sedation method in these patients.
-
Aliment. Pharmacol. Ther. · May 2003
Review Comparative StudySystematic review: Antacids, H2-receptor antagonists, prokinetics, bismuth and sucralfate therapy for non-ulcer dyspepsia.
Evidence for the effectiveness of antacids, histamine-2 receptor antagonists, bismuth salts, sucralfate and prokinetic therapy in non-ulcer dyspepsia is conflicting. ⋯ The meta-analyses suggest that histamine-2 receptor antagonists and prokinetics are superior to placebo. These data are difficult to interpret, however, as funnel plot asymmetry suggests that the magnitude of the effect could be due to publication bias or other heterogeneity-related issues.
-
Aliment. Pharmacol. Ther. · May 2003
Diverticular disease of the colon--on the rise: a study of hospital admissions in England between 1989/1990 and 1999/2000.
Diverticular disease emerged as a common problem in Western countries over the course of the 20th century. ⋯ Admission rates for diverticular disease increased over the study period. The proportion of patients who underwent operation increased, but in-patient and population mortality rates remained unchanged. With an ageing population, diverticular disease will become an increasingly important clinical problem in England.
-
Aliment. Pharmacol. Ther. · Apr 2003
Therapeutic value of a gastroenterology consultation in irritable bowel syndrome.
Functional patients comprise the largest group in gastroenterology practice. Pharmacological therapy of irritable bowel syndrome is disappointing. One treatment strategy for irritable bowel syndrome emphasizes the physician's role; the physician is promoted as the therapeutic modality. ⋯ A consultation itself is a therapeutic intervention in irritable bowel syndrome with regard to its impact on societal economic burden. It is associated with a durable decrease in illness-specific health care utilization. It may not address all aspects of irritable bowel syndrome; multiple domains of morbidity demonstrated persistent distress.
-
Aliment. Pharmacol. Ther. · Mar 2003
Predictors of conventional and alternative health care seeking for irritable bowel syndrome and functional dyspepsia.
The drivers of conventional and, especially, alternative health care use for irritable bowel syndrome and functional dyspepsia are not clear. ⋯ Psychological morbidity did not predict conventional or alternative health care use for gastrointestinal symptoms. Other factors were more important.