Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Aug 2014
Mortality after total colectomy in 3084 patients with inflammatory bowel disease: a population-based cohort study.
A high post-operative mortality has been reported following colectomy in patients with inflammatory bowel disease (IBD), especially in some patient groups. ⋯ The 40-day mortality following total colectomy in IBD patients in Sweden is low, except in patients ≥59 years old.
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Aliment. Pharmacol. Ther. · Aug 2014
Clinical TrialEfficacy of the neurokinin-1 receptor antagonist aprepitant in children with cyclical vomiting syndrome.
Aprepitant (Emend, Merck Sharp & Dohme Ltd, Haarlem, the Netherlands), a neurokinin-1 receptor antagonist, prevents vomiting in a range of conditions. No data are available on its use in children with cyclical vomiting syndrome (CVS). ⋯ Aprepitant appears effective for both acute and prophylactic management of paediatric cyclical vomiting syndrome refractory to conventional therapies.