Paediatric and perinatal epidemiology
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Paediatr Perinat Epidemiol · Jan 2014
Variation by diagnostic subtype in risk for autism spectrum disorders associated with maternal parity among Finnish births.
Associations between maternal parity and outcomes in offspring may provide evidence for involvement of prenatal exposures. The objective of this study was to determine whether risk for autism spectrum disorders (ASD) is associated with maternal parity. ⋯ Differences in patterns of association between maternal parity and ASD subtypes may indicate varying contributions of specific environmental factors to risk; however, differences in diagnosis or in treatment seeking for childhood behavioural problems cannot be ruled out, particularly for higher functioning cases.
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Paediatr Perinat Epidemiol · Jan 2014
Predicting risk of spontaneous preterm delivery in women with a singleton pregnancy.
Prediction of a woman's risk of a spontaneous preterm delivery (PTD) is a core challenge and an unresolved problem in today's obstetric practice. The objective of this study was to develop prediction models for spontaneous PTD (<37 weeks). ⋯ Spontaneous PTD is difficult to predict in multiparous women and nearly impossible in primiparous, by using this statistical method in a large and unselected sample. However, adding clinical data (like cervical length) may in the future further improve its predictive performance.