Archives of gynecology and obstetrics
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Arch. Gynecol. Obstet. · Feb 2009
Case ReportsA case of benign metastasizing leiomyoma treated by surgical castration followed by an aromatase inhibitor, anastrozole.
Benign metastasizing leiomyoma (BML) is a rare disease most often located in the lungs of women with a history of surgery for benign leiomyoma of the uterus. Optimum therapy for BML, has not been established. We report here an additional case of BML in the lung that was successfully treated with surgical castration followed by hormonal therapy with anastrozole, an aromatase inhibitor. ⋯ In addition to castration by bilateral oophorectomy or gonadotropin-releasing hormone agonist, the use of aromatase inhibitor is one of the treatment options for the further suppression of peripheral estrogen production in these patients.