Brain injury : [BI]
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Brain injury : [BI] · Dec 2000
Multicenter Study Comparative StudyThe clinical value of serum S-100 protein measurements in minor head injury: a Scandinavian multicentre study.
This study of patients with minor head injury was designed to investigate the relation of S-100 protein measurements to computed tomograpy (CT) findings and patients outcomes. Increased serum levels of this protein were hypothetized to predict intracranial pathology and increased frequency of post-concussion symptoms. ⋯ Undetectable serum level of S-100 protein predicts normal intracranial findings on CT scan. Determination of S-100 protein in serum may be used to select patients for CT scanning. Increased S-100 serum levels may be more related to post-concussion symptoms caused by mild traumatic brain injury than to symptoms of psychological origin.