Brain injury : [BI]
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Brain injury : [BI] · May 2006
Predictive value of S-100B protein and neuron specific-enolase as markers of traumatic brain damage in clinical use.
S-100B and NSE proteins are considered to be neurobiochemical markers for the brain damage. The aim of this study was to consider the diagnostic and prognostic validity of the initial serum levels of S-100B and NSE in clinical use. ⋯ The clear correlation between S-100B and NSE serum concentrations and CCT findings does not validate both markers as an independent predictor of diagnosis and prognosis of brain injury.