Brain injury : [BI]
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Brain injury : [BI] · Jan 2010
Review Meta AnalysisMagnesium sulphate in the management of patients with aneurysmal subarachnoid haemorrhage: a meta-analysis of prospective controlled trials.
Experimental and clinical studies have suggested that magnesium has neuroprotective and vasodilatation properties. A meta-analysis was conducted to assess the effectiveness and safety of intravenous magnesium therapy in patients with aneurysmal subarachnoid haemorrhage (SAH). ⋯ The meta-analysis suggests that intravenous magnesium therapy reduces the risk of DCI and poor outcome after aneurysmal SAH. Serum magnesium should be routinely monitored for both effectiveness and safety considerations.
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Brain injury : [BI] · Jan 2010
ReviewAcute management of acquired brain injury part I: an evidence-based review of non-pharmacological interventions.
To review the literature on non-pharmacological interventions used in acute settings to manage elevated intracranial pressure (ICP) and minimize cerebral damage in patients with acquired brain injury (ABI). ⋯ There is a paucity of information regarding non-pharmacological acute management of patients with ABI. Strong levels of evidence were found for only four of the seven interventions (decompressive craniectomy, cerebrospinal fluid drainage, hypothermia and hyperbaric oxygen) and only for specific components of their use. Further research into all interventions is warranted.
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Brain injury : [BI] · Jan 2010
Multicenter StudyFunctional level during sub-acute rehabilitation after traumatic brain injury: course and predictors of outcome.
To describe the functional level during sub-acute rehabilitation after moderate and severe traumatic brain injury (TBI) and to evaluate the impact of pre-injury and injury-related factors as predictors of early recovery. ⋯ Less than half of moderate TBI patients reached a normal functional level at discharge from sub-acute rehabilitation. A short PTA period, a high GCS score and FIM score at admission to rehabilitation and a longer stay in the rehabilitation unit were positive predictors of functional level at discharge.
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Brain injury : [BI] · Jan 2010
Initial validation of a brief provisional diagnostic scale for delirium.
The Delirium Diagnostic Tool-Provisional (DDT-Pro) is a newly developed provisional diagnostic tool for delirium presented here. This study evaluated its accuracy and validity in a population of participants with acquired brain injury (ABI). ⋯ The DDT-Pro is supported as a measure of delirium following ABI. Further validation in ABI and other medical populations is recommended.
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Brain injury : [BI] · Jan 2010
Multicenter StudyUse of brain electrical activity to quantify traumatic brain injury in the emergency department.
To validate a QEEG algorithm on traumatic brain injury in an Emergency Department (ED) setting. ⋯ The TBI discriminant index appears to be a sensitive index of brain function. It may be used to suggest whether or not a patient presenting with altered mental status requires a CT scan. This index may aid in the triage of such patients in the ED. Such an easy to use, automated system may greatly enhance the clinical utility of EEG in the ED.