Brain injury : [BI]
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Brain injury : [BI] · Jan 2013
Changes in intrinsic functional brain networks following blast-induced mild traumatic brain injury.
Blast-induced mild traumatic brain injuries (mTBI) commonly go undetected by computed tomography and conventional magnetic resonance imaging (MRI). This study was used to investigate functional brain network abnormalities in a group of blast-induced mTBI subjects using independent component analysis (ICA) of resting state functional MRI (fMRI) data. ⋯ The results suggest white matter disruption across certain attentional networks. Additionally, given their elevated activity relative to controls', the temporo-parietal junctions of blast mTBI subjects may be compensating for diffuse axonal injury in other cortical regions.
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Brain injury : [BI] · Jan 2013
Multiple traumatic brain injury and concussive symptoms among deployed military personnel.
To identify if concussive symptoms occur with greater frequency among military personnel with multiple lifetime TBIs and if a history of TBI increases risk for subsequent TBI. ⋯ Among deployed military personnel, the relationship of previous TBI with recent TBI and concussive symptoms may be largely explained by the presence of psychological symptoms.
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Brain injury : [BI] · Jan 2013
ReviewThe current role of decompressive craniectomy in the management of neurological emergencies.
Decompressive craniectomy has been used as a lifesaving procedure for many neurological emergencies, including traumatic brain injury, ischaemic stroke, subarachnoid haemorrhage, cerebrovenous thrombosis, severe intracranial infection, inflammatory demyelination and encephalopathy. The evidence to support using decompressive craniectomy in these situations is, however, limited. Decompressive craniectomy has only been evaluated by randomized controlled trials in traumatic brain injury and ischaemic stroke and, even so, its benefits and risks in these situations remain elusive. If one considers a modified Rankin Scale of 4 or 5 or dependency in daily activity as an unfavourable outcome, decompressive craniectomy is associated with an increased risk of survivors with unfavourable outcome (relative risk [RR] = 2.9, 95% confidence interval [CI] = 1.5-5.8, p = 0.002, I(2 )= 0%; number needed to operate to increase an unfavourable outcome = 3.5, 95% CI = 2.4-7.4), but not the number of survivors with a favourable outcome (RR = 1.5, 95% CI = 0.9-2.6, p = 0.13, I(2 )= 0%).
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Brain injury : [BI] · Jan 2013
Comparative Study Controlled Clinical TrialEffects of dexmedetomidine on cerebral blood flow in critically ill patients with or without traumatic brain injury: a prospective controlled trial.
To examine the effect of dexmedetomidine on CBF in critical ill patients with or without TBI. ⋯ Dexmedetomidine may be used in patients with TBI without risk of affecting brain oxygenation.
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Brain injury : [BI] · Jan 2013
Factor structure of the Depression Anxiety Stress Scales in individuals with traumatic brain injury.
The Depression Anxiety Stress Scales (DASS) and its shorter version, the DASS21, demonstrate a consistent factor structure. However, when these scales are used with people with traumatic brain injury (TBI), it is possible that TBI symptoms that overlap with anxiety and depression (e.g., irritability, inertia, emotional lability) result in changes to the underlying structure. This study aimed to establish whether the factor structure of the DASS and DASS21 when used with individuals with TBI is consistent with the three scales designated in the manual. ⋯ These results indicate that it may be preferable to use the full DASS, rather than the DASS21, with individuals with TBI.