Brain injury : [BI]
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Brain injury : [BI] · Jan 2016
Community integration questionnaire: Outcomes of people with traumatic brain injury and high support needs compared with multiple matched controls.
To determine level of community integration in adults with traumatic brain injury and high support needs (TBI-HSN) compared with multiple matched controls. ⋯ Normative CIQ data has enabled meaningful comparisons of the community integration of adults with chronic TBI to the general population in Australia. Evidence makes clear with numeric precision that individuals with TBI and high support needs are much less integrated than their non-TBI counterparts despite living in the community for many years.
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Brain injury : [BI] · Jan 2016
Low-dose levetiracetam for seizure prophylaxis after traumatic brain injury.
The primary objective of this study was to determine the effectiveness of a lower dose of levetiracetam (500 mg every 12 hours) to prevent early seizures after traumatic brain injury (TBI). It was hypothesized that the seizure rate would be low and comparable to previous studies using phenytoin. ⋯ A lower dose of levetiracetam 500 mg every 12 hours after TBI may be effective for early seizure prevention after TBI.
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Brain injury : [BI] · Jan 2016
Volumetric and morphometric MRI findings in patients with mild traumatic brain injury.
This study compared cortical and sub-cortical volumes between patients with complicated (i.e. presence of intracranial abnormality on the day-of-injury CT) and uncomplicated (i.e. absence of intracranial abnormality) mild traumatic brain injury (MTBI) 4 weeks post-injury. The study hypothesized regionally decreased brain volumes and reduced cortical thickness in patients with complicated MTBIs compared with uncomplicated MTBI. ⋯ The study findings suggest that the classification of complicated and uncomplicated MTBI may be too broad to differentiate volumetric and morphometric effects of injury in the early post-injury phase.
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Brain injury : [BI] · Jan 2016
Cognitive reserve and persistent post-concussion symptoms--A prospective mild traumatic brain injury (mTBI) cohort study.
Having three or more persisting (i.e. > 3 months) post-concussion symptoms (PCS) affects a significant number of patients after a mild traumatic brain injury (mTBI). A common complaint is cognitive deficits. However, several meta-analyses have found no evidence of long-term cognitive impairment in mTBI patients. The study sought to answer two questions: first, is there a difference in cognitive performance between PCS and recovered mTBI patients? Second, is lower cognitive reserve a risk factor for developing PCS? ⋯ mTBI may be linked to subtle executive memory deficits. Lower cognitive reserve appears to be a risk factor for PCS and indicates individual vulnerabilities.
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Brain injury : [BI] · Jan 2016
Reducing head computed tomography after mild traumatic brain injury: Screening value of clinical findings and S100B protein levels.
The present prospective study was performed to investigate whether primary clinical findings and serum S100B concentrations at 3 and 6 hours post-trauma can contribute to the selection of patients for an initial computed tomography (CT) scanning. ⋯ Serum S100B measurement along with clinical evaluation of patients with mild traumatic brain injury has promising screening value to support selection of patients for CT scanning.