International journal of geriatric psychiatry
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Int J Geriatr Psychiatry · Oct 2017
Randomized Controlled TrialRivastigmine patch reduces the incidence of postoperative delirium in older patients with cognitive impairment.
To date, data regarding the efficacy of acetylcholinesterase inhibitors in preventing postoperative delirium (POD) are inconsistent and conflicting. Older individuals with cognitive dysfunction are thought to show POD more frequently. Our aim was to study the effectiveness of rivastigmine prophylaxis on the incidence, severity, and risk factors for POD in older patients with cognitive impairment undergoing hip fracture surgery. ⋯ Perioperative rivastigmine patch application could reduce the occurrence of POD in older patients with low cognitive status. Copyright © 2016 John Wiley & Sons, Ltd.