International journal of geriatric psychiatry
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Int J Geriatr Psychiatry · Oct 2020
Prospective longitudinal evaluation of cytokines in mild cognitive impairment due to AD and Lewy body disease.
We conducted a prospective longitudinal study of plasma cytokines during the Mild Cognitive Impairment (MCI) stage of Lewy body disease and Alzheimer's disease, hypothesizing that cytokine levels would decrease over time and that this would be correlated with decline in cognition. ⋯ Peripheral inflammation decreased in both disease groups during MCI suggesting this may be a therapeutic window for future anti-inflammatory agents.
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Int J Geriatr Psychiatry · Oct 2020
Neuropsychiatric symptoms as a distinguishing factor between memory diagnoses.
To determine whether neuropsychiatric symptoms (NPS) are able to differentiate those with mild cognitive impairment (MCI) and dementia from persons who are cognitively healthy. ⋯ The present study's results demonstrate that specific NPS are differentially represented among types of cognitive impairment and establish the predictive value for one of these cognitive impairment diagnoses.