The Korean journal of internal medicine
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Korean J. Intern. Med. · Mar 2014
Randomized Controlled TrialEvaluation of the effect of D-002, a mixture of beeswax alcohols, on osteoarthritis symptoms.
Nonsteroidal anti-inflammatory drugs relieve osteoarthritis (OA) symptoms but cause adverse effects. D-002, a mixture of beeswax alcohols, is effective against experimental OA. A pilot study found that D-002 (50 mg/day) for 8 weeks improves OA symptoms. The aim of this study was to investigate the effects of D-002 (50 to 100 mg/day) administered for 6 weeks on OA symptoms. ⋯ These results indicate that D-002 (50 to 100 mg/day) for 6 weeks ameliorated arthritic symptoms and was well tolerated.
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Korean J. Intern. Med. · Mar 2014
Observational StudyEffect of renin-angiotensin-system blockers on contrast-medium-induced acute kidney injury after coronary angiography.
With the increasing incidence of cardiovascular disease, angiocardiography using contrast-enhancing media has become an essential diagnostic and therapeutic tool, despite the risk of contrast-medium-induced acute kidney injury (CIAKI). CIAKI may be exacerbated by renin-angiotensin-system (RAS) blockers, which are also used in a variety of cardiovascular disorders. This study evaluated the effects of RAS blockade on CIAKI after coronary angiography. ⋯ This study showed that the incidence of CIAKI was increased in patients treated with RAS blockers.