Journal of clinical epidemiology
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To describe the inaugural comparative effectiveness research (CER) cohort study of Washington State's Comparative Effectiveness Research Translation Network (CERTAIN), which compares invasive with noninvasive treatments for peripheral artery disease, and to focus on the patient centeredness of this cohort study by describing it within the context of a newly published conceptual framework for patient-centered outcomes research (PCOR). ⋯ The CERTAIN's inaugural cohort study may serve as a useful model for conducting PCOR and creating a learning health care network.