Clinical rehabilitation
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Clinical rehabilitation · Jun 2010
Randomized Controlled TrialDoes low-dose botulinum toxin help the recovery of arm function when given early after stroke? A phase II randomized controlled pilot study to estimate effect size.
Spasticity after stroke may be associated with worse functional outcome. Our study aim is to establish whether a low dose of botulinum toxin, given early post stroke before clinically evident spasticity warrants treatment, will improve recovery of arm function. ⋯ Individuals with no arm function within three weeks of stroke may benefit functionally from botulinum toxin. Using the effect size of 0.5, further studies would need a minimum of 101 participants in each group to confirm this finding.
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Clinical rehabilitation · Jun 2010
Randomized Controlled TrialThe development and feasibility of a ward-based physiotherapy and nutritional rehabilitation package for people experiencing critical illness.
To investigate ward-based rehabilitation after critical illness and undertake a pilot study exploring the feasibility of delivering enhanced physiotherapy and nutritional rehabilitation. ⋯ This feasibility pilot work has informed the design of a larger study to evaluate enhanced rehabilitation following critical illness.