Nutrition
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Randomized Controlled Trial
Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients.
Inflammation mediators have been recognized as risk factors for the pathogenesis of coronary artery disease (CAD). The purpose of this study was to investigate the effect of L-carnitine supplementation (LC, 1000 mg/d) on inflammation markers in patients with CAD. ⋯ We suggest that LC supplementation, due to its antioxidant effects, may have potential utility to reduce inflammation in CAD.
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Randomized Controlled Trial
Effect of an advanced glycation end product-restricted diet and exercise on metabolic parameters in adult overweight men.
The aim of this study was to review the effect of a low advanced glycation end product (AGEs) diet, exercise, and a combination of both on circulating AGE levels as well as on plasma lipids and anthropometric parameters. ⋯ An AGE-restricted diet reduces serum AGE and indices of body fat. The addition of exercise to the restricted diet has the same effects but also improves lipid profile.
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Increased plasma selenium is associated with better outcomes in children with systemic inflammation.
The aim of this study was to assess the effects of changes in plasma selenium on the outcome of critically ill children. ⋯ An increase in plasma selenium is independently associated with shorter times of ventilation and ICU stay in children with systemic inflammation. These findings raise the hypothesis that selenium supplementation could be beneficial in children with critical illnesses.
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To measure concentrations of β-carotene and lycopene in the breast milk of healthy, well-nourished, lactating women supplemented with fresh carrot or tomato paste. ⋯ We suggest that breast milk carotenoid levels reflect the mother's level of intake and can thus be raised by simple nutritional intervention. The results of this study may be relevant to breast-feeding mothers of both preterm and term infants by raising antiinflammatory and antioxidant properties in their milk.
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The aim of this study was to evaluate the effects of long-term energy restriction (ER) on plasma, liver, and skeletal muscle metabolite profiles in aging rats fed a Western-style diet. ⋯ Although steatosis was reduced, the beneficial effects of ER on systemic insulin resistance and plasma and skeletal muscle metabolites observed elsewhere with a balanced diet seem to be compromised by high-sucrose and low ω-3 PUFA intake.