American journal of physical medicine & rehabilitation
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Am J Phys Med Rehabil · May 2002
Randomized Controlled Trial Comparative Study Clinical TrialBotulinum toxin in upper limb spasticity after acquired brain injury: a randomized trial comparing dilution techniques.
To compare the efficacy of two different volume preparations of the same dose of botulinum toxin-A in relieving spasticity in wrist and finger flexors secondary to acquired brain injury. ⋯ Because this preliminary study found no difference in spasticity reduction between high- and low-volume preparations of a 60-unit dose of botulinum toxin-A, a larger-sample study seems warranted to compare the efficacy of high-volume and low-volume preparations.