American journal of physical medicine & rehabilitation
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Am J Phys Med Rehabil · Apr 2003
Comparative StudyEffect of botulinum toxin type A on cerebral palsy with upper limb spasticity.
The objective of this study was to investigate the effects of botulinum toxin type A injections in reducing upper limb muscular spasticity and in improving motor function in children with cerebral palsy. ⋯ Our findings support the premise that botulinum toxin type A injections are effective in reducing upper limb spasticity and in improving movement pattern and fine motor function of patients with spastic cerebral palsy. A reduction in caregivers' burden and improved quality of life were demonstrated through the study period.