Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America
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Infect Control Hosp Epidemiol · Sep 2011
Outcomes and genetic relatedness of carbapenem-resistant enterobacteriaceae at Detroit medical center.
Carbapenem-resistant Enterobacteriaceae (CRE) are rapidly emerging in hospitals in the United States and are posing a significant threat. To better understand the transmission dynamics and the acquisition of resistant strains, a thorough analysis of epidemiologic and molecular characteristics was performed. ⋯ In this large U.S. cohort of patients with CRE infection, which reflects the modern continuum of medical care, co-colonization with CRE and A. baumannii or P. aeruginosa was associated with increased mortality. Two predominant clones of K. pneumoniae accounted for the majority of cases of CRE infection.
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Infect Control Hosp Epidemiol · Sep 2011
High incidence of multidrug-resistant gram-negative bacteria recovered from Afghan patients at a deployed US military hospital.
To investigate potential sources and risks associated with multidrug-resistant (MDR) bacteria in a deployed US military hospital. ⋯ Gram-negative bacteria from Afghan patients had high rates of antimicrobial resistance. Patients experiencing complex trauma and prolonged hospital stays likely contribute to the presence of MDR bacteria in this facility. However, many of these patients had community-acquired cases, which implies high rates of colonization prior to hospital admission.