Social psychiatry and psychiatric epidemiology
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Soc Psychiatry Psychiatr Epidemiol · Sep 2021
Associations between neighborhood greenspace and brain imaging measures in non-demented older adults: the Cardiovascular Health Study.
Greater neighborhood greenspace has been associated with brain health, including better cognition and lower odds of Alzheimer's disease in older adults. We investigated associations between neighborhood greenspace and brain-based magnetic resonance imaging (MRI) measures and potential effect modification by sex or apolipoprotein E genotype (APOE), a risk factor for Alzheimer's disease. ⋯ This study suggests a possible association between greater greenspace and less ventricular enlargement, a measure reflecting global brain atrophy. If confirmed in other longitudinal cohort studies, interventions and policies to improve community greenspaces may help to maintain brain health in older age.