Journal of cardiology
-
Journal of cardiology · Jun 2021
Drug repurposing? Cardiovascular effect of colchicine on patients with coronary artery disease: A systematic review and meta-analysis.
Patients with coronary artery disease (CAD) are at high risk of atherosclerotic events. The aim of this meta-analysis is to evaluate the cardiovascular protective effect of colchicine on patients with CAD. ⋯ This meta-analysis shows that there is a decreased composite risk of MI and restenosis after PCI with the use of colchicine in patients with CAD. However, colchicine did not appear beneficial for all-cause mortality, and it led to a higher risk of GI events.