Journal of investigative surgery : the official journal of the Academy of Surgical Research
-
Comparative Study
A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats.
This study investigated the effects of metamizole and paracetamol on pain and oxidative stress induced by scalpel incision and carrageenan in rats. ⋯ Our results show that metamizole is more effective than paracetamol for treating surgical trauma-related pain, inflammation, and oxidative stress and hence may be a preferential drug to paracetamol.