Current opinion in infectious diseases
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Curr. Opin. Infect. Dis. · Jun 2008
ReviewEffectiveness of impregnated central venous catheters for catheter related blood stream infection: a systematic review.
Clinicians need information on the relative effectiveness of different types of impregnated central venous catheter for serious infection and their relative costs and adverse effects in order to decide which type, if any, to use. ⋯ The most promising options for reducing catheter-related blood stream infection are heparin-coated or antibiotic-impregnated central venous catheters. Large, high-quality randomized controlled trials are needed to evaluate which of these methods is most effective for reducing clinically important consequences of catheter-associated infection.