Current opinion in infectious diseases
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Curr. Opin. Infect. Dis. · Aug 2009
ReviewPrevention and treatment of invasive fungal diseases in neutropenic patients.
Despite advances in the diagnosis and management, invasive fungal diseases contribute substantially to the morbidity and mortality of patients with prolonged neutropenia. ⋯ With the validation of preemptive strategies in clinical trials, we will likely have evidence-based targeted use of antifungals. PCR-based techniques are also promising tools for preemptive strategies and are undergoing evaluation. Knowledge of host genetic factors may be important in stratifying the risk for fungal disease during periods of high risk.