Current opinion in infectious diseases
-
Curr. Opin. Infect. Dis. · Aug 2010
ReviewPrevention of healthcare-associated infections in children: new strategies and success stories.
Attention to patient safety has made hospital infection prevention and control strategies a subject of increasing focus from healthcare personnel, patients and families, accrediting organizations, and government. This review highlights recent literature and new successes in the prevention of healthcare-associated infections in children. ⋯ A renewed interest in infection prevention by multiple stakeholders has energized our field and contributed to impressive successes in reducing rates of healthcare-associated infections. Nevertheless, important knowledge gaps remain and an emphasis on funding of high-quality, rigorous studies to answer unresolved questions will be critical to our efforts to further prevent infections for hospitalized children.
-
Curr. Opin. Infect. Dis. · Aug 2010
ReviewMultiresistant Acinetobacter baumannii infections: epidemiology and management.
We present recent data about epidemiology of Acinetobacter baumannii in the hospital setting, major resistance mechanisms, and therapeutic options for infections caused by multidrug-resistant strains. ⋯ The optimal treatment for multidrug-resistant A. baumannii nosocomial infections has not been established. Carbapenems are the mainstay of treatment in susceptible isolates. Colistin and tigecycline retain good in-vitro activity and in many cases represent the only therapeutic options.